SMITH BARRY,CORDON CARDO CARLOS,PETRYLAK DANIEL,DOMENECH JOSEP,MARTIN MIREIA CASTILLA
申请号:
IN8062/DELNP/2013
公开号:
IN2013DN08062A
申请日:
2013.09.13
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention provides inter alia a method for identifying an agent that selectively decreases the number of cancer stem cells (CSCs). This method includes (a) contacting a CSC from a population of cells with a candidate agent and (b) determining whether the candidate agent reduces the survival or growth of the CSC or increases differentiation of the CSC relative to a CSC that has not been contacted with the candidate agent. The method may be used as a high throughput screen.