To provide a method for producing a medicine-containing particle of high density with a non-gelation polymer as a base.SOLUTION: A method for producing a medicine-containing particle has the following steps: (A) a non-gelation polymer and a medicine are dissolved and/or dispersed in an aqueous component, to obtain a liquid composition, (B) the liquid composition is sprayed and cooled and solidified, to obtain a frozen particle, and (C) the frozen particle is dried at -5 to 30°C at the product temperature.SELECTED DRAWING: None【課題】非ゲル化性高分子を基剤とする高密度な薬物含有粒子の製造方法を提供する。【解決手段】次の工程(A)、(B)及び(C):(A)非ゲル化性高分子及び薬物を水性成分に溶解及び/又は分散し、液状組成物を得る工程、(B)前記液状組成物を噴霧及び冷却固化し、凍結粒子を得る工程、並びに(C)前記凍結粒子を品温-5~30℃で乾燥する工程を含む、薬物含有粒子の製造方法。【選択図】 なし