Provided is a clip treatment device that can reliably hold the state once a clip has been applied, and can remove a clip placed in a living body at an arbitrary timing. The clip treatment instrument has a clip body having two arms facing each other and opening and closing, and a folded portion connecting the base ends of the two arms, A tubular holding tube for closing the two arms and accommodating the clip body therein, a connecting member for connecting the clip body and the operation wire, and urging the connecting member from the proximal end to the distal end side with respect to the holding tube And a biasing member to perform. The holding tube has a locked portion, the connecting member has a locking portion, and the connecting member moves from the distal side to the proximal side according to the movement of the operation wire from the distal side to the proximal side, The locking portion is locked to the locked portion, and the connecting member is locked to the holding tube.一旦、クリップが適用された後は、その状態を確実に保持することができ、かつ、生体内に留置されたクリップを任意のタイミングで取り外すことができるクリップ処置具を提供する。クリップ処置具は、互いに対向し、かつ開閉する２つの腕部および２つの腕部の基端部を接続する折り返し部を有するクリップ本体と、先端側から基端側へのクリップ本体の移動に従って２つの腕部を閉じて内部にクリップ本体を収容する筒状の押え管と、クリップ本体と操作ワイヤとを連結する連結部材と、連結部材を押え管に対して基端側から先端側に付勢する付勢部材とを備える。押え管は、被係止部を有し、連結部材は、係止部を有し、先端側から基端側への操作ワイヤの移動に従って、連結部材が先端側から基端側に移動し、係止部が被係止部に係止されて、連結部材が押え管にロックされる。
