PEPTIDES BH4 STABILISÉS ET LEURS UTILISATIONS

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专利权人:

Inc.;Dana-Farber Cancer Institute

发明人:

申请号：

EP19179053.4

公开号：

EP3572422A1

申请日:

2014.03.14

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Provided herein are polypeptides containing stabilized BH4 domains of BCL-2 family proteins that are capable of binding and/or inactivating and/or modulating BAX protein, and/or its close homologues BAK and BOK, and/or other physiological BH4 targets. Also provided are compositions containing these polypeptides and methods of treating cytotoxic diseases that include administering to a subject one of the polypeptides.

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中国工程科技知识中心

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http://www.ckcest.cn/home/