MIN, YUN SIKKR,민연식,SHIM, SUNG BOKR,심성보,KIM, MIN SEOKKR,김민석
申请号：
KR1020120143953
公开号：
KR1020140075524A
申请日:
2012.12.11
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
The present invention provides a novel method for manufacturing a cis-form nucleoside. More specifically, the present invention relates to a method for manufacturing lamivudine which synthesis (2R,5R)-2-isopropyl-5-methylphenyl 5-ethoxy-1,3-oxatiolran-2-carboxylate as an intermediate. The manufacturing method of the present invention has a relatively simple process and yield for each manufacturing step is high.COPYRIGHT KIPO 2014본 발명은 새로운 시스형 뉴클레오시드 제조방법을 제공한다. 본 발명의 제조방법은 입체선택적으로 효율적인 반응에 의해 상업적 생산에도 적합하다는 장점을 갖는다.
