Summary "solid substrates for attenuating or preventing adhesion and vascularization of tissues and cells" This invention provides solid substrates for attenuating or preventing adhesion and / or vascularization of cells or tissues, whose solid substrate comprises a derivative of the marine organism skeleton and is characterized by a fluid specific absorption capacity value of less than 40%, whose fluid specific absorption capacity value is determined by establishing a spontaneous fluid absorption value divided by a total fluid absorption value and processes. for the selection of a solid substrate based marine organism skeleton derivative optimized to attenuate or prevent cell and tissue adhesion and / or vascularization and application thereof. This invention also provides solid substrates for attenuating or preventing adhesion and / or vascularization of cells or tissues whose solid substrate is characterized by having a contact angle value greater than 60 degrees when in contact with a fluid. This invention also provides solid substrates for attenuating or preventing adhesion and / or vascularization of cells or tissues whose solid substrate is characterized by minimal surface roughness (ra) or substantial surface smoothness as measured by scanning electron microscopy or light microscopy. Atomic force The invention also provides methods for the selection of a coral based solid substrate optimized to attenuate or prevent cell and tissue adhesion and / or vascularization and applications thereof.resumo “substratos sólidos para atenuar ou prevenir a adesão e vascularização de tecidos e células” esta invenção fornece substratos sólidos para atenuar ou prevenir a adesão e/ou vascularização de células ou de tecidos, cujo substrato sólido compreende um derivado do esqueleto de organismo marinho e é caracterizado por um valor de capacidade de absorção específica de fluido inferior a 40%, cujo valor de capacidade de absorção específica de fluido é determinado através do e