PROBLEM TO BE SOLVED: To provide an anagenesis substrate excellent in invasiveness of cell, and suitable for regeneration of normal tissue.SOLUTION: There is provided a tissue regeneration substrate comprising a nonwoven fabric composed of a bioabsorbable material. Concerning the tissue regeneration substrate, in the nonwoven fabric, the median value of a fiber diameter distribution is 1.0-8.0 μm, and the variation coefficient is 40% or higher.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】細胞の侵入性に優れ、かつ、正常な組織の再生に好適な組織再生基材を提供する。【解決手段】生体吸収性材料からなる不織布からなる組織再生基材であって、前記不織布は、繊維径分布の中央値が1.0~8.0μm、かつ、変動係数が40%以上である組織再生基材。【選択図】 なし