PROBLEM TO BE SOLVED: To provide a stable percutaneous absorption preparation for percutaneous absorption of donepezil or hydrochloride salt thereof that, even at pasting, suppresses any drop of cohesion force of a pressure sensitive adhesive layer and that also suppresses any adhesive residue by cohesion failure at stripping off.SOLUTION: The percutaneous absorption preparation is characterized by having the pressure sensitive adhesive layer containing 2-[(1-benzyl-4-piperidinyl)methyl]-5,6-dimethoxyindan-1-one and/or its hydrochloride salt and a metal chloride, the pressure sensitive adhesive layer being crosslinked.COPYRIGHT: (C)2013,JPO&INPIT【課題】ドネペジルまたはその塩酸塩を経皮吸収させるための経皮吸収型製剤であって、貼付時においても粘着剤層の凝集力の低下を生じにくく、剥離除去の際の凝集破壊による糊残りの生じにくい安定な経皮吸収製剤を提供すること。【解決手段】粘着剤層に2-[(1-ベンジル-4-ピペリジニル)メチル]-5,6-ジメトキシインダン-1-オンおよび/またはその塩酸塩と金属塩化物とを含み、粘着剤層が架橋されていることを特徴とする経皮吸収製剤。【選択図】なし
