WINUM, Jean-Yves,MONTERO, Jean-Louis,KÖHLER, Stephan
申请号：
ES09768167
公开号：
ES2639745T3
申请日:
2009.11.10
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
Compounds of the following general formula (la): in which X represents an N characterized in that - the phenyl group is substituted by n group (s) YB, varying n from 1 to 5, said group YB being such that: - Y represents a linear or branched, saturated or unsaturated alkylene group, comprising from 1 to 6 carbon atoms, preferably from 2 to 4 carbon atoms, and - B represents a group selected from: - an aryl or heteroaryl group, particularly a phenyl group or naphthyl - a C5-C10 heterocyclic group, preferably C5-C6, comprising 1 to 6 heteroatoms chosen from the elements of the family of the chalcogens and the pnitogens, and - a C3-C6 cycloalkyl group, said group B being substituted by one or several substituent (s), preferably by a substituent, said substituent (s) being chosen from the group comprising: or a halogen atom, or an alkoxy group comprising from 1 to 4 carbon atoms, or an aryloxy group, particularly a phenyloxy group or a linear, branched or cyclic, saturated or unsaturated alkyl group, comprising 1 to 6 carbon atoms, preferably 2 to 4 carbon atoms, optionally substituted by one or more halogen atoms, or an aryl group, preferably a phenyl group, optionally substituted by a C1-C4 alkyl, or a hydroxyl group, or a thiol group, or an amine group, or an amide group, or a carboxylic acid group, or a cyano group, or an azide group, and a nitro group, said compounds being in the form of a racemate, of any one of their enantiomers or of any of the different tautomers corresponding to said racemates and enantiomers, as well as in the form of their pharmaceutically acceptable salts.Compuestos de la siguiente fórmula general (la): en la que X representa un N caracterizados porque - el grupo fenilo está sustituido por n grupo(s) Y-B, variando n de 1 a 5, siendo dicho grupo Y-B tal que: - Y representa un grupo alquileno lineal o ramificado, saturado o insaturado, que comprende de 1 a 6 átomos de carbono, preferiblemente de 2 a 4 átomos de carbono, y - B representa un gru
