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PROCEDE DE REDUCTION ET/OU D'EXTRACTION DE FXI ET DE FXIA DE SOLUTIONS CONTENANT LESDITS FACTEURS DE COAGULATION
专利权人:
OCTAPHARMA AG
发明人:
SCHULTZ, PETRA,GRUBER, GERHARD,BAL, FREDERIC,MARKS, FRANK,WINGE, STEFAN
申请号:
CA2817096
公开号:
CA2817096A1
申请日:
2011.11.16
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
A process for reduction and/or removal of FXI and FXIa from a source solution containing said coagulation factors and as main components immunoglobulins comprising the following steps: a) contacting the FXI and/or FXIa containing solution with an affinity chromatographic gel wherein heparin or heparan is linked to the matrix material; b) allowing adsorption of FXI and/or FXIa and c)separation of the liquid deprived of FXI and/or FXIa from the adsorption media.
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