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A PROCESS FOR REDUCTION AND/OR REMOVAL OF FXI AND FXIA FROM SOLUTIONS CONTAINING SAID COAGULATION FACTORS
专利权人:
发明人:
SCHULTZ PETRA,GRUBER GERHARD,BAL FREDERIC,MARKS FRANK,WINGE STEFAN
申请号:
IN3829/DELNP/2013
公开号:
IN2013DN03829A
申请日:
2013.04.30
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
A process for reduction and/or removal of FXI and FXIa from a source solution containing said coagulation factors and as main components immunoglobulins comprising the following steps: a) contacting the FXI and/or FXIa containing solution with an affinity chromatographic gel wherein heparin or heparan is linked to the matrix material b) allowing adsorption of FXI and/or FXIa and c)separation of the liquid deprived of FXI and/or FXIa from the adsorption media.
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