Hasslacher, Meinhard,Citkowicz, Andrzej,White, Catherine,Franke, Ken
申请号:
AU2017202050
公开号:
AU2017202050A1
申请日:
2017.03.28
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
#$%^&*AU2017202050A120170420.pdf#####ABSTRACT The present application provides stabilized formulations of furin (e.g., rfurin) containing a sugar, sugar alcohol, and/or non-ionic surfactant. As compared to non-stabilized compositions, the furin formulations disclosed herein retain greater amounts of furin activity and monomeric furin content, while reducing furin aggregation when stored and/or subjected to mechanical stress. Also provided are methods for stably diluting furin (e.g., rfurin) compositions.