Hasslacher, Meinhard,Citkowicz, Andrzej,White, Catherine,Franke, Ken
申请号:
AU2012261813
公开号:
AU2012261813A1
申请日:
2012.06.04
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present application provides stabilized formulations of furin (e.g., rfurin) containing a sugar, sugar alcohol, and/or non-ionic surfactant. As compared to non-stabilized compositions, the furin formulations disclosed herein retain greater amounts of furin activity and monomeric furin content, while reducing furin aggregation when stored and/or subjected to mechanical stress. Also provided are methods for stably diluting furin (e.g., rfurin) compositions.