The invention relates to a device for treatment of a tissue (8) of a living being, including a transducer (4) for emitting a beam of ultrasound waves mounted on a movable treatment head (1), an ultrasonic imaging device (2, 3), optionally an inflatable balloon (5) surrounding the treatment head (1) and containing a coupling fluid, and a control unit for controlling the movement of the treatment head (1) and the operation of the transducer (4) and the imaging device (2, 3), wherein the treatment head (1) is adjustable to at least two of a treatment position (T), a monitoring position (M) and a travel position (S) in order to avoid displacement of tissues (7, 8) during displacement of the treatment head (1) an increase imaging quality.