A method for inhibiting the production of cytokines of T helper cell type II (Th2 cell) and/or inhibiting the production of chemokines in a mammal is provided, wherein the method comprises administrating to the mammal an effective amount of an active component selected from a group consisting of a compound of formula (I), pharmaceutically acceptable salts and esters of the compound, and combinations thereof:一種用於抑制第二型T輔助細胞之細胞激素之生成及/或抑制趨化激素之生成之醫藥組合物,其係包含一有效量之活性成分,其中該活性成分係選自以下群組:式(I)化合物、其醫藥可接受鹽及酯、或前述之組合:;(I)。;一種使用式(I)化合物及/或其醫藥可接受鹽及/或酯在製造藥劑之應用。