A pharmaceutical composition for inhibiting at least one of histone gene transcription and histone expression is provided. The pharmaceutical composition comprises an effective amount of an active component selected from a group consisting of a compound of formula (I), a pharmaceutically acceptabie salt of the compound, and combinations thereof:一種用於抑制組蛋白基因轉錄及抑制組蛋白表現之至少一者之醫藥組合物,其係包含一有效量之活性成分,該活性成分係選自以下群組:式(I)化合物、式(I)化合物之醫藥可接受鹽、及前述之組合: