BROWN, Sean P.,GONZALEZ BUENROSTRO, Ana,LI, Yunxiao,LI, Zhihong,LIZARZABURU, Mike Elias,LUCAS, Brian S.,PARAS, Nick A.,TAYGERLY, Joshua,VIMOLRATANA, Marc,WANG, Xianghong,YU, Ming,ZANCANELLA, Manuel,ZH
申请号:
TN2017000067
公开号:
TN2017000067A1
申请日:
2015.08.28
申请国别(地区):
TN
年份:
2018
代理人:
摘要:
Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, (I) and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.