Sung Wuk Kim,Sung Soo Jun,Seung Kook Park,Song Young Kim,Eun Sun Kim,Jae Kap Jeong,Ha Na Kim,Yeon Jung Song
申请号:
US13513803
公开号:
US08618045B2
申请日:
2011.12.21
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Provided is a modified human tumor necrosis factor receptor-1 polypeptide or a fragment thereof that binds to a tumor necrosis factor in vivo or ex vivo. The modified human tumor necrosis factor receptor-1 polypeptide or fragment exhibits improved ability to bind tumor necrosis factor and resistance to proteases.