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Tumour-associated peptides which bind to MHC molecules
专利权人:
IMMATICS BIOTECHNOLOGIES GMBH
发明人:
TRAUTWEIN CLAUDIA,RAMMENSEE HANS-GEORG,STEVANOVIC STEFAN,WEINSCHENK TONI
申请号:
SI200531543
公开号:
SI2058323T1
申请日:
2005.05.24
申请国别(地区):
SI
年份:
2012
代理人:
摘要:
Tumor-associated peptide having a 9-17 residue amino acid sequence from the groups SEQ ID-No. 1-577 from a given sequence protocol. The peptide has the ability to bond with a molecule of the human class I major histocompatibility complex (MHC) proteins. At least one amino acid is chemically modified, or at least one amino acid is deleted, or at least one amino acid is replaced by another amino acid with similar chemical characteristics. Tumor-associated peptide having a 9-17 residue amino acid sequence from the groups SEQ ID-No. 1-577 from a given sequence protocol. The peptide has the ability to bond with a molecule of the human class I major histocompatibility complex (MHC) proteins. At least one amino acid is chemically modified, or at least one amino acid is deleted, or at least one amino acid is replaced by another amino acid with similar chemical characteristics. The N and/or C terminal is available of at least one other amino acid. ACTIVITY : Cytostatic. No biological data is given. MECHANISM OF ACTION : None given.
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