Polymeric micellar clusters and their use in drugs

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专利权人:

ユニバーシティー カレッジ ロンドン

发明人:

ユカブ イゲオマ エフ,サーツェリン アンドリス ジー,フー スエリアン

申请号：

JP2009523342

公开号：

JP5469458B2

申请日:

2007.08.08

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

Polymeric micellar clusters formed from amphiphilic carbohydrate polymers and their uses in formulating drugs is disclosed, and in particular the finding that amphiphilic carbohydrate polymers are capable of self assembling to form micellar clusters in which the carbohydrate amphiphiles aggregate into hierarchically organized micellar clusters of individual aggregates. The micellar clusters may be transformed into stable nanoparticles with drugs, especially hydrophobic drugs that have poor aqueous solubility, and may improve the transfer of hydrophobic drugs across biological barriers.

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中国工程科技知识中心

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