PROTÉINE DE FUSION AYANT DES FONCTIONS DOUBLES POUR INHIBER L'ANGIOGENÈSE DANS UN MICROENVIRONNEMENT TUMORAL ET ACTIVER UNE RÉPONSE IMMUNE ADAPTATIVE, ET GÈNE ET UTILISATION DE CETTE PROTÉINE

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专利权人:

CHINA PHARMACEUTICAL UNIVERSITY

发明人:

WANG, SHUZHEN,CHEN, YIJUN,HE, DONGYANG,LIU, NAN,MA, CHAO,GAO, ZHENYUE

申请号：

EP14795356

公开号：

EP2995626A4

申请日:

2014.05.05

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

Disclosed are bifunctional fusion proteins having Tumstatin active fragments and CD137L extracellular regions. The proteins exhibit activities to inhibit the proliferation of human umbilical vein endothelial cells and to costimulate the proliferation of T cells. They can be used for the treatment of various tumor-related diseases and the regulation of angiogenesis and immunological effects in humans.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/