Jenkins, Russell W.,Barbie, David,Paweletz, Cloud P.,Ivanova, Elena,Aref, Amir
申请号：
AU2018243568
公开号：
AU2018243568A1
申请日:
2018.03.30
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
Provided herein are methods for evaluating tumor cell spheroids in a three-dimensional microfluidic device by determining changes in the relative levels of live cells and dead cells in aliquots cultured under different conditions. Methods described herein allow ex vivo recapitulation of the tumor microenvironment such that the in vivo effectiveness of a test compound in treating tumor tissue may be predicted.
