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ADHESIVE PEEL-FORMING FORMULATIONS FOR DERMAL DELIVERY OF DRUGS AND METHODS OF USING THE SAME
专利权人:
ZARS PHARMA; INC.
发明人:
ZHANG, JIE,WARNER, KEVIN, S.,ASHBURN, MICHAEL, A.,RIGBY, LARRY, D.,NIU, SUYI
申请号:
EP05760457
公开号:
EP1753380A4
申请日:
2005.06.07
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention is drawn to adhesive peel-forming formulations for dermal delivery of a drug. The formulation can include a drug, a solvent vehicle, and a peel-forming agent. The solvent vehicle can include a volatile solvent system having one or more volatile solvent, and a non-volatile solvent system having one or more non-volatile solvent, wherein the non-volatile solvent system has a solubility for the drug that is within a window of operable solubility for the drug such that the drug can be delivered at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified peelable layer after at least a portion of the volatile solvent system is evaporated.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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