Emma Hickman;Stuart Milstein;Anne-Marie Pulichino;Andrew Sprague;Gregory Hinkle;Antonin De Fougerolles;John L. Diener
发明人:
Antonin De Fougerolles,John L. Diener,Emma Hickman,Gregory Hinkle,Stuart Milstein,Anne-Marie Pulichino,Andrew Sprague
申请号：
US13090580
公开号：
US08344127B2
申请日:
2011.04.20
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC.
