Robert Kendall Morrison;Karen Jane Meyrick Morrison;Pia M. Challita-Eid;Rene S. Hubert;Mary Faris;Arthur B. Raitano;Aya Jakobovits;Wangmao Ge
发明人:
Aya Jakobovits,Arthur B. Raitano,Mary Faris,Rene S. Hubert,Wangmao Ge,Karen Jane Meyrick Morrison,Robert Kendall Morrison,Pia M. Challita-Eid
申请号:
US13153336
公开号:
US08562989B2
申请日:
2011.06.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 161P2F10B can be used in active or passive immunization.