Mary Faris;Pia M. Challita-Eid;Arthur B. Raitano;Aya Jakobovits;Wangmao Ge
发明人:
Arthur B. Raitano,Pia M. Challita-Eid,Aya Jakobovits,Mary Faris,Wangmao Ge
申请号：
US12651336
公开号：
US08604169B2
申请日:
2009.12.31
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A novel gene 251P5G2 and its encoded protein, and variants thereof, are described wherein 251P5G2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 251P5G2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 251P5G2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response； antibodies or T cells reactive with 251P5G2 can be used in active or passive immunization.
