Raitano, Arthur B.,Challita-Eid, Pia M.,Jakobovits, Aya,Faris, Mary,Ge, Wangmao
申请号:
AU2008202217
公开号:
AU2008202217B2
申请日:
2008.05.20
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2008202217B220120726.pdf#####ABSTRACT A novel gene 191 P4D 12(b) and its encoded protein, and variants thereof, are described wherein 191P4D12(b) exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 191 P4D 12(b) provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 191P4D12(b) gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 191P4D12(b) can be used in active or passive immunization.'