LEARMONTH, DAVID ALEXANDER,KISS, LASZLO ERNO,LEAL PALMA, PEDRO NUNO,DOS SANTOS FERREIRA, HUMBERTO,ARAUJO SOARES DA SILVA, PATRÍCIO MANUEL VIEIRA,LEARMONTH DAVID ALEXANDER,KISS LASZLO ERNO,LEAL PALMA PEDRO NUNO,DOS SANTOS FERREIRA HUMBERTO,ARAUJO S
申请号：
ES06769520
公开号：
ES2545178T3
申请日:
2006.07.26
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
A compound of formula (I): ** Formula ** in which R1 and R2 are independently of each other hydrogen； X represents a methylene group； Y represents an oxygen or sulfur atom； n represents the number 0, 1, 2 or 3 and m represents the number 0 or 1； R3 represents a pyridine N-oxide group according to formula A, B or C, which is connected as indicated by the unlabeled link: ** Formula ** where R4, R5, R6 and R7 independently of each other they represent hydrogen, C1-C6 alkyl, C1-C6 thioalkyl, C1-C6 alkoxy, C6-C12 aryloxy or a C6-C12 thioaryl group, C1-C6 alkanoyl or a C7-C13 aroyl group, amino, C1-C6 alkylamino, dialkylamino C1-C6, C3-C12 cycloalkylamino or C3-C12 heterocycloalkylamino, C1-C6 alkylsulfonyl or C6-C12 arylsulfonyl, halogen, C1-C6 haloalkyl, trifluoromethyl, cyano, nitro or a heteroaryl group； or where two or more of the R4, R5, R6 and R7 moieties taken together represent aliphatic or heteroaliphatic rings or aromatic or heteroaromatic rings and in which P represents a central unit selected from 1,2,4-oxadiazol-3 regioisomers, 5-diyl and 1,3,4-oxadiazol-2,5-diyl, and wherein the central unit regioisomers include both regioisomers achievable by exchanging the nitrocatechol moiety and the moiety - (X) n- (Y) m -R3.Un compuesto de fórmula (I):**Fórmula** en la que R1 y R2 son independientemente el uno del otro hidrógeno； X representa un grupo metileno； Y representa un átomo de oxígeno o azufre； n representa el número 0, 1, 2 o 3 y m representa el número 0 o 1； R3 representa un grupo N-óxido de piridina de acuerdo con la fórmula A, B o C, que está conectado según se indica mediante el enlace no marcado:**Fórmula** donde R4, R5, R6 y R7 independientemente el uno del otro representan hidrógeno, alquilo C1-C6, tioalquilo C1-C6, alcoxi C1-C6, ariloxi C6-C12 o un grupo tioarilo C6-C12, alcanoílo C1-C6 o un grupo aroílo C7-C13, amino, alquilamino C1-C6, dialquilamino C1-C6, cicloalquilamino C3-C12 o heterocicloalquilamino C3-C12, alquilsulfonilo C1-C6 o arilsulfonilo
