具抗雄激素性質新芳醯胺衍生物农业专利-农业学术服务平台

发明人:: RATILAINEN, JARI,拉提赖能　杰瑞,拉提賴能　傑瑞,KOISTINAHO, MILLA,科伊斯汀阿荷　米拉,MUONA, ANU,穆欧纳　亚纽,穆歐納　亞紐,拉提赖能杰瑞,拉提賴能傑瑞,科伊斯汀阿荷米拉,穆欧纳亚纽,穆歐納亞紐

摘要：: The invention relates to novel arylamide derivatives having formula (I)and stereoisomers and pharmaceutically acceptable salts thereof, where R2, R8, R9 and R11 are as defined in the claims. The arylamide derivatives of formula (I) have antiandrogenic properties. The invention also relates to compounds of formula (I) for use as a medicament and to pharmaceutical compositions comprising them and to their preparation.本發明係相關於具有分子式(I)之新芳醯胺衍生物以及其立體異構物與藥學上可接受之鹽類，其中R2、R8、R9與R11係如同申請專利範圍中所定義的。分子式(I)之芳醯胺衍生物具有抗雄激素性質。本發明亦相關於作為藥物用途的分子式(I)之化合物與相關於包含它們的藥學組成物以及相關於其製備。