您的位置: 首页 > 农业专利 > 详情页

A PROCESS FOR PREPARTION OF PHENYLCYCLOBUTYLAMIDE DERIVATIVES EREOISOMERS, THE PREPARATION PROCESSES AND USES THEREOF
专利权人:
发明人:
ZHAO SHUQIANG,WEN SHOUMING,DING HAO,YAN YASHI,CHEN XIAOPING
申请号:
IN1328/MUMNP/2010
公开号:
IN271900B
申请日:
2010.06.22
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
Phenylcyclobutylamide derivatives and their optical isomers, the preparing processes and the uses thereof, which includes the compounds of formula (I), their pure stereoisomers and their pharmaceutically acceptable salts. In formula (I), R is H, formacyl, acetyl, haloacetyl, benzoyl, benzyloxy carbonyl (Cbz), t-butoxy carbonyl (Boc), or 9-fluorenyl methoxyl carbonyl (Fmoc). The present novel compounds have pharmaceutical activity and are prepared by condensation reaction of racemic, levo- or dextro- demethyl Sibutramine and racemic or D/L isoleucine under a mild condition. It is demonstrated that the present compounds have effect of losing weight to obese mode rats in different level and the effect is better than Sibutramine by the animal experiments. So the medicaments prepared by the present compounds or the medicaments prepared by the compositions of the present compounds and other pharmaceutical activity compounds may be used for treating obesity.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充