The invention relates to novel arylamide derivatives having formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, where R1 - R11, R', R'', z and X are as defined in the claims. The arylamide derivatives of formula (I) have antiandrogenic properties. The invention also relates to compounds of formula (I) for use as a medicament and to pharmaceutical compositions comprising them and to their preparation.本發明與具有結構式(I)的新芳醯胺衍生物；以及其立體異構物與藥學上可接受的鹽類有關，其中R1 - R11、R’、R’’、z以及X為如申請專利範圍中所定義者。結構式(I)的芳醯胺衍生物具有抗雄性素性質。本發明亦與將結構式(I)的化合物使用作為藥劑有關以及與包含它們的藥學組成物以及涉及其製備有關。
