It is something regarding the capsule which includes the pellet of the active material where this invention has the active material where two differs at least and differs, as for the active material it differs in regard to the discharge profile in the alimentary canal. These active materials the vitamin, the mineral substance, the microelement, the unsaturated fatty acid, amino acid and/or are chosen from the plant extract and the group which consists of the substance. The discharge profile which differs is fast, it is displayed in and/or by the melting of the active material pellet which will be been slow. This control discharge in the alimentary canal, intended oriented absorption of the active material is brought to the absorption territory which differs. Following to this invention, the medicine shape which is manufactured with even in case of very many available active materials, makes that bio availability is improved high-level possible.本発明は少なくとも2つの異なる活性物質を有する異なる活性物質のペレットを含むカプセルに関するものであり、活性物質は消化管におけるその放出プロフィールに関して異なる。これらの活性物質はビタミン、ミネラル物質、微量元素、不飽和脂肪酸、アミノ酸並びに/又は植物抽出物及び物質からなる群より選ばれる。異なる放出プロフィールは素早い、中程度の及び/又はゆっくりとした活性物質ペレットの溶解によって表される。この制御放出は消化管における異なる吸収領域へ活性物質の目的指向型吸収をもたらす。本発明に従って調製される剤形は、非常に多くの利用可能な活性物質の場合でさえ、バイオアベイラビリティが高度に改善されることを可能にする。