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CYCLIC AMINO COMPOUNDS
专利权人:
ДАЙИТИ САНКИО КОМПАНИ; ЛИМИТЕД (JP)
发明人:
НАКАО Акира (JP),ГОТАНДА Кентоку (JP),АОКИ Казумаса (JP),ХИРАНО Симпей (JP),ХИРУМА Йосихару (JP),СИИКИ Такеси (JP)
申请号:
RU2011130928/04
公开号:
RU2011130928A
申请日:
2009.12.22
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. The compound represented by the following formula (I), or a pharmaceutically acceptable salt thereof: wherein in the presented formula each group of substituents is defined as follows: R represents a hydrogen atom, a hydroxy group, a halogen atom, a C1-C6 alkyl group, a C1-C6 alkoxy group, a halogen C1-C6 alkyl a group, a halogen C1-C6 alkoxy group or an aryl group, R and R, are identical or different from each other, and represent a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a C1-C6 alkoxy group, a halogen C1-C6 alkyl group, a halogen C1-C6 alkoxy group or a cyano group, R represents a C1-C6 alkyl group or a halogen C1-C6 alkyl group, A represents a single bond, a substituted phenylene group or a vinylene group, B represents a single bond, an oxygen atom or a sulfur atom, Ar represents an aryl group which is optionally substituted by a group, selected from the group consisting of a halogen atom, a cyano group, a C1-C6 alkyl group, a C1-C6 alkoxy group, a halogen C1-C6 alkyl group and a halogen C1-C6 alkoxy group, Z is —COOH, —SONHR or a tetrazolyl group, R is th hydrogen atom or a C1-C6 alkyl group, and m is 0, 1, 2, 3, 4, 5 or 6.2. A compound according to claim 1, or a pharmaceutically acceptable salt thereof, wherein R1 is a hydrogen atom. The compound according to claim 1 or a pharmaceutically acceptable salt thereof, wherein R and R, which are the same or different from each other, are a hydrogen atom, a fluorine atom, a chlorine atom, a cyano group, a methyl group, a methoxy group, an ethoxy group, a trifluoromethyl group or a trifluoromethoxy group. . The compound according to claim 1 or a pharmaceutically acceptable salt thereof, wherein A is pr�1. Соединение, представленное следующей формулой (I), или его фармацевтически приемлемая соль:где в представленной формуле каждая группа заместителей определена следующим образом:Rпредставляет собой атом водорода, гидроксигруппу, атом галогена, C1-C6алкильную группу, C1-C6алкоксигруппу, галогенC1-C6алкиль
来源网站:
中国工程科技知识中心
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