PURRO, NORBERT,SMYTH, MARK,GOLDMAN, ERICK,WIRTH, DAVID D.
申请号：
CA3015208
公开号：
CA3015208A1
申请日:
2013.06.03
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystallineforms, solvates and pharmaceutically acceptable salts thereof. Also disclosedare pharmaceuticalcompositions that include the Btk inhibitor, as well as methods of using theBtk inhibitor, alone or incombination with other therapeutic agents, for the treatment of autoimmunediseases or conditions,heteroimmune diseases or conditions, cancer, including lymphoma, andinflammatory diseases orconditions.
