David D. Wirth;Mark Smyth;Norbert Purro;Erick Goldman
发明人:
Mark Smyth,Erick Goldman,David D. Wirth,Norbert Purro
申请号：
US13908949
公开号：
US20130338172A1
申请日:
2013.06.03
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
