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Process for cyclooxygenase-2 selective inhibitor
专利权人:
Dharmesh Mahendra Shah;Viral Narendra Jariwala;Sanjay Amratlal Solanki;Ashok Vasantray Vyas;Ashokkumar Bhikhubhai Mistry
发明人:
Dharmesh Mahendra Shah,Sanjay Amratlal Solanki,Viral Narendra Jariwala,Ashok Vasantray Vyas,Ashokkumar Bhikhubhai Mistry
申请号:
US13885522
公开号:
US08841457B2
申请日:
2011.11.15
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention describes a process for preparing a cyclooxygenase-2 selective inhibitor. It provides a synthetic procedure for the said substance namely 5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine of formula (I). The invention also relates to preparation of a new intermediate of formula (IV) and a process to prepare it. Furthermore, the invention describes a process for preparing another key intermediate of formula (II). Compounds of formula (IV) and formula (II) are useful intermediates in synthesis of the said cyclooxygenase-2 inhibitor.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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