A PROCESS FOR CYCLOOXYGENASE-2 SELECTIVE INHIBITOR

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专利权人:

VIRDEV INTERMEDIATES PVT. LTD.

发明人:

SHAH, Dharmesh Mahendra,SOLANKI, Sanjay Amratlal,JARIWALA, Viral Narendra,VYAS, Ashok Vasantray,MISTRY, Ashokkumar Bhikhubhai

申请号：

MYPI 2013700782

公开号：

MY163379A

申请日:

2011.11.15

申请国别(地区):

MY

年份:

2017

代理人:

摘要：

The present invention describes a process for preparing a cyclooxygenase-2 selective inhibitor. It provides a synthetic procedure for the said substance namely 5-chloro-3-(4-methylsulphonyl) phenyl-2-(2-methyl-5-pyridinyl) pyridine of formula (I). The invention also relates to preparation of a new intermediate of formula (IV) and a process to prepare it. Furthermore, the invention describes a process for preparing another key intermediate of formula (II). Compounds of formula (IV) and formula (II) are useful intermediates in synthesis of the said cyclooxygenase-2 inhibitor.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/