Gerardo Rodriguez-Araujo,Stephen R. Puckett, SR.,Stephen R. Puckett, JR.,Mitchell W. Puckett
申请号：
US16688944
公开号：
US20200215114A1
申请日:
2019.11.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A composition for delivering cargo to cytoplasm of a cell, wherein the cargo treats oncological disorders. In one embodiment the composition comprises: an exosome； and cargo, located within the exosome, comprising at least one plasmid. In another embodiment the composition comprises: an exosome； and cargo, located within the exosome, comprising a at least one plasmid. Wherein the cargo transduces autologous T cells into Chimeric Antigen Receptor T cells (CAR-T cells), which comprise at least one antigenic target.
