Mutants resistant to proteases Active FC antibody

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专利权人:

JANSSEN BIOTECH; INC.

发明人:

STROHL, WILLIAM,JORDAN, ROBERT,BREZSKI, RANDALL

申请号：

CR20130292

公开号：

CR20130292A

申请日:

2013.06.17

申请国别(地区):

CR

年份:

2013

代理人:

摘要：

The present invention relates to modified Fc-containing molecules including modified antibodies characterized by increased resistance to host and pathogen-derived proteases, ability to interact with Fc&gamma；R receptors except with Fc&gamma；RI, and lack of induction of IL-10 secretion by macrophages, and methods of using and making them.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/