Protease resistant modified erythropoietin polypeptides

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专利权人:

Manuel Vega;Thierry Guyon;Rene Gantier;Lila Drittanti

发明人:

Rene Gantier,Manuel Vega,Lila Drittanti,Thierry Guyon

申请号：

US12157150

公开号：

US08114839B2

申请日:

2008.06.06

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Modified erythropoietin polypeptides that include the mutation R131Q, and uses thereof are provided. Also provided are pharmaceutical compositions, including compositions formulated for oral administration, that contain the modified erythropoietin polypeptides and uses of the compositions to treat diseases and conditions treated by erythropoietin.

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