ACTIVE PROTEASE-RESISTANT ANTIBODY FC MUTANTS

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专利权人:

发明人:

申请号：

EP11851794.5

公开号：

EP2654780A1

申请日:

2011.12.15

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention relates to modified Fc-containing molecules including modified antibodies characterized by increased resistance to host and pathogen-derived proteases, ability to interact with Fc&gammaR receptors except with Fc&gammaRI, and lack of induction of IL-10 secretion by macrophages, and methods of using and making them.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/