Refers to a Solid oral Pharmaceutical composition comprising: (a) to agomelatine or N - [2 - (7 - methoxy 1-naphthylacetamide in an amount of 0.1 - 25 mg (b) a polyol or a diluent Agent such as saccharide (c) excipients such as aglutinates, dispersion agents, LUBRICANTS, Recovery agents Coating, plasticizers, anti irritants, Sweeteners, Flavourings, among others.This composition allows for a slow release of agomelatine and a higher bioavailability.SE REFIERE A UNA COMPOSICION FARMACEUTICA BUCAL SOLIDA QUE COMPRENDE: (A) AGOMELATINA O N-[2-(7 METOXI-1-NAFTILACETAMIDA EN UNA CANTIDAD DE 0,1 - 25 MG (B) UN AGENTE DILUYENTE TALES COMO POLIOL O UN SACARIDO (C) EXCIPIENTES TAL COMO AGLUTINATES, AGENTES DE DISPERSION, LUBRICANTES, AGENTES DE RECUBRIMIENTO, PLASTIFICANTES, AROMATIZANTES, CONTRA-IRRITANTES, EDULCORANTES ENTRE OTROS. DICHA COMPOSICION PERMITE OBTENER UNA LIBERACION LENTA DE LA AGOMELATINA Y UNA MAYOR BIODISPONIBILIDAD.
