BLAQUIERE NICOLE,DUDLEY DANETTE,HEALD ROBERT,JONES MARK,NDUBAKU CHUDI,PRICE STEPHEN,WANG LAN,DO STEVEN,FOLKES ADRIAN JOHN,HEFFRON TIMOTHY,KOLESNIKOV ALEKSANDR,OLIVERO ALAN G,STABEN STEVEN
申请号：
ZA201202199
公开号：
ZA201202199B
申请日:
2012.03.26
申请国别(地区):
ZA
年份:
2013
代理人:
摘要：
The invention relates to benzoxazepin compounds of Formula I including stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof, wherein: Z 1 is CR 1 or N； Z 2 is CR 2 or N； Z 3 is CR 3 or N； Z 4 is CR 4 or N； and B is a pyrazolyl, imidazolyl, or triazolyl ring which compounds have anti-cancer activity, and more specifically, inhibit PI3 kinase activity.
