including stereoisomers, salts and tautomers thereof, wherein R1a, R1b, R2a, R2b, R2c, R2d, R2e, R2f, R2g, R2h, R2i, R2j, R2k, R2l, R2m, R2n, R2o, R2p, R2q, R2r and R2s are as defined herein. Methods associated with preparation and use of such compounds are also provided.