BLAQUIERE, NICOLE,DO, STEVEN,DUDLEY, DANETTE,FOLKES, ADRIAN J.,HEALD, ROBERT,HEFFRON, TIMOTHY,JONES, MARK,KOLESNIKOV, ALEKSANDR,NDUBAKU, CHUDI,OLIVERO, ALAN G.,PRICE, STEPHEN,STABEN, STEVEN,WANG, LAN
申请号:
SG2012021747
公开号:
SG179670A1
申请日:
2010.09.27
申请国别(地区):
SG
年份:
2012
代理人:
摘要:
The invention relates to benzoxazepin compounds of Formula (I) including stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof, wherein: Z1 is CR1 or N Z2 is CR2 or N Z3 is CR3 or N Z4 is CR4 or N and B is a pyrazolyl, imidazolyl, or triazolyl ring which compounds have anti-cancer activity, and more specifically, inhibit PI3 kinase activity.