FIELD: medicine； pharmaceuticals.SUBSTANCE: invention relates to use of the compound of formula (1) and a pharmaceutical composition based thereon for treating or preventing seborrheic keratosis, where X is CO, CHOZ or CHNRZ； Z is selected from hydrogen； unbranched and branched (C1-C6) alkyl； unbranched or branched (C2-C6) alkenyl； unbranched or branched (C2-C6) alkynyl； (C3-C8) cycloalkyl； (C6-C24) aryl； (C7-C24) aralkyl； m- and p-CH2(C6H4)COSM； COR3； CSR3； C(NR6)R3； SOR4； SO2R3R3N； SO2OM； SO2NR7R8； SO2O-artemisinyl； SO2NH-artemisinyl； POR4R5； PSR4R5； and SO2R3； R3 is selected from unbranched or branched (C1-C6) alkyl； unbranched or branched (C1-C6) alkoxy； unbranched or branched (C2-C6) alkenyl； unbranched or branched (C2-C6) alkynyl； (C3-C8) cycloalkyl； (C6-C24) aryl； (C6-C10) aryloxy； (C7-C24) aralkyl； - (CH2)n-OCO, where n is integer from 1 to 6； and 10α-di-hydro-artemisilil； R4 and R5 are independently selected from unbranched or branched (C1-C6) alkyl； unbranched or branched (C2-C6) alkenyl； unbranched or branched (C2-C6) alkynyl； (C3-C8) cycloalkyl； (C6-C24) aryl； (C7-C24) aralkyl； OM； unbranched or branched (C1-C6) alkoxy； (C6-C10) aryloxy； and NR7R8； R6 is selected from unbranched or branched (C1-C6) alkyl； unbranched or branched (C2-C6) alkenyl； unbranched or branched (C2-C6) alkynyl； (C3-C8) cycloalkyl； (C6-C24) aryl； and (C7-C24) aralkyl； M is hydrogen or a pharmaceutically acceptable cation； R7 and R8 are independently selected from unbranched or branched (C1-C6) alkyl, or R7 and R8 together form (C4-C6) alkylene bridge； and R is selected from hydrogen； unbranched or branched (C1-C6) alkyl； unbranched or branched (C2-C6) alkenyl； unbranched or branched (C2-C6) alkynyl； (C3-C8) cycloalkyl； (C6-C24) aryl； and (C7-C24) aralkyl.(1)EFFECT: technical result is the new prescription of known compounds which can be used in medicine for treating or preventing seborrheic keratosis.18 cl, 2 dwg, 1 tbl, 1 exИзобретение относится к применению соединения формулы (1)
