PROBLEM TO BE SOLVED: To provide compounds useful as therapeutic agents for disease involving metabotropic glutamate receptor subtype 2 and/or metabotropic glutamate receptor subtype 3.SOLUTION: The invention provides compounds represented by formula (1) or pharmaceutically acceptable salts thereof. [n is 1 or 2; LA is a bond or the like; ring A is a C6-10 aromatic carbocycle or the like; LB is -O-, -C(O)-NH-, -NH-C(O)-, or the like; ring B is a 5-10 membered aromatic heterocycle or the like; R1 and R2 are H, C1-4 alkyl, or the like; R3, R4 and R5 are H, C1-6 alkyl, or the like; R6, R7 and R8 are C1-6 alkyl, -C(O)-NRaRb, -NRd-C(O)-Rc, or the like; Ra and Rb are H, C1-4 alkyl, or the like; Rc is C1-4 alkyl or the like; and Rd is H or the like.]SELECTED DRAWING: NoneCOPYRIGHT: (C)2020,JPO&INPIT【課題】代謝型グルタミン酸受容体サブタイプ2及び/又は代謝型グルタミン酸受容体サブタイプ3が関与する疾患の治療剤として有用な化合物の提供。【解決手段】式(1)で表される化合物又はその製薬学的に許容される塩。[nは1又は2;LAは結合等;環AはC6-10芳香族炭素環等;LBは-O-、-C(O)-NH-又は-NH-C(O)-等;環Bは5から10員の芳香族複素環等;R1及びR2はH又はC1-4アルキル等;R3、R4及びR5は、H又はC1-6アルキル等;R6、R7及びR8は、C1-6アルキル、-C(O)-NRaRb又は-NRd-C(O)-Rc等;Ra及びRbはH又はC1-4アルキル等;RcはC1-4アルキル等;RdはH等を表す]【選択図】なし