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PROMEDICAMENTS DE RILUZOLE ET LEUR UTILISATION
专利权人:
BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD.
发明人:
WROBEL, JAY EDWARD,REITZ, ALLEN B.,PELLETIER, JEFFERY CLAUDE,SMITH, GARRY ROBERT,BIAN, HAIYAN
申请号:
CA2978158
公开号:
CA2978158A1
申请日:
2016.02.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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