HORSLEY, HELEN TRACEY,MADDEN, JAMES,REUBERSON, JAMES THOMAS,ROWLEY, JULIAN HUGH
申请号：
CA2999929
公开号：
CA2999929A1
申请日:
2016.09.28
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
A series of substituted pyrido[3,2-d]pyrimidine and 1,5-naphthyridine derivatives of formula (I), as defined herein, being selective inhibitors of phosphatidylinositol-4-kinase IIIß (PI4KIIIß) activity, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders viral diseases and malaria and organ and cell transplant rejection.
