Helen Tracey Horsley,James Madden,James Thomas Reuberson,Julian Hugh Rowley
申请号：
US15762454
公开号：
US20180273525A1
申请日:
2016.09.28
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A series of substituted pyrido[3,2-d]pyrimidine and 1,5-naphthyridine derivatives of formula (I), as defined herein, being selective inhibitors of phosphatidylinositol-4-kinase IIIβ (PI4KIIIβ) activity, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders viral diseases and malaria and organ and cell transplant rejection.
